Chisels & Bits has a lot of different features that use useful in cutting down on how much time it takes to design your custom blocks, keep this in mind when you're making something new there's usually more than one way to accomplish something.
You can undo most bit/chisel operations, creative block destruction included. These commands can be invaluable if your building something and accidentally click on the wrong thing, or make a wrong move.
This means that you can bind undo/redo, or specific modes to mouse buttons or keyboard keys allowing you to skip the radial menu and spend more time chiseling
This lets you combine different parts of various blocks together and work with larger portions without having to build everything in one block.
Depending on what your doing one mode might be more useful than another, and remembers that the radial menu works for bits, postive designs, tape measures as well for chisels
If you use the wrench on a west face, the block will rotate around the east - west axis, it's all about which face you click on.
For instance you can make a pillar, then you can cut up a pillar into four corners and apply it in new ways.
This lets you quickly copy your work and make more of the different parts you need when building allowing you to focus on the larger aspects rather than having to redo the designs you have already completed, you can also use the postiive pattern's placment mode to skip the crafting step.
This removes any extra rotation, placement information from the block allowing you to stack more effectively.